Neuroscience Reagents and Kits
Cell Signaling Technology Doublecortin F6K9E Rabbit mAb Alexa FluorR 488 Conjugate 100 ul
Doublecortin F6K9E Rabbit mAb Alexa FluorR 488 Conjugate 100 ul
Cayman Chemical ResolvIn D1 AChE Tracer 100dtn
A chromogenicBxylosidase substrate upon hydrolysis byBxylosidase 4-nitrophenol is released which can be quantified by colorimetric detection at 405 nm as a measure ofBxylosidase activity
Cayman Chemical Latnoprost AChE Tracer 500dtn
A multi-kinase inhibitor inhibits VEGFR2 PDGFRB FLT3 and c-Kit (IC50s 1.12 0.13 0.63 and 0.14 nM respectively) and is selective for these kinases over RET and AMPKa1 (IC50s 74.1 and 352.2 nM respectively) inhibits VEGF-induced proliferation of HUVECs (IC50 31 nM) decreases VEGF-induced capillary tube formation in HUVECs at 1 UM reduces FBS-induced migration of HUVECs at 0.01 or 0.1 UM reduces tumor volume and growth alone and in combination with gefitinib in an HCC827 NSCLC mouse xenograft model at 80 mg/kg per day
Cayman Chemical CyclIc AMP AChE Tracer 500dtn
A steroidal glycoside with diverse biological activities reduces the proliferation of LNCaP and T47D cancer cells (IC50s 32.1 and 27.5 UM respectively) inhibits TNF-a-induced nuclear translocation of NF-KB in HaCaT keratinocytes at 50 nM decreases AST serum levels in a mouse model of carbon tetrachloride-induced liver injury at 0.1 mg/kg topical administration reduces ear epidermal thickness and scaling as well as leukocyte and macrophage infiltration in an imiquimod-induced mouse model of psoriasis at 5 mg/kg
Cayman Chemical CyclIc AMP AChE Tracer 100dtn
A PDE3 inhibitor (IC50 0.4 nM) selective for PDE3 over PDE4 (IC50 1479 nM) reduces the phytohemagglutinin-induced proliferation of isolated human monocytes inhibits LPS-induced increases of TNF-a protein levels in isolated human monocytes (IC50 520 nM) increases cAMP levels in isolated human neutrophils at 10 UM inhibits electric field stimulation-induced contractile responses in isolated guinea pig trachea in a concentration-dependent manner intranasal administration inhibits histamine-induced bronchoconstriction and tracheal edema in guinea pigs at 25 w/w
Biotium Alpha-Bungarotoxin CF488A
Fluorescent conjuates of -Bungarotoxin bind to the nicotinic acetylcholine receptor with high affinity, and thus can be used to image the distribution of the receptor at the neuromuscular junctions. CF dyes are Biotium's line of next-generation fluorescent dyes with advantages in brightness, photostability, and conjugate specificity compared to other fluorescent dyes. Green fluorescent CF488A dye (Ex/Em 490/515 nm) is a superior alternative to FITC (fluorescein) due to its exceptional brightness and photostability.